Fluorolintane See also References Navigation menu58838621Interactive image10.1002/dta.168925044512"Analytical Report - Fluorolintane"10.1016/j.bmc.2009.03.02519345586"Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury""Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression"10.1021/ja01110a033eexpanding ite

Designer drugsDissociative drugsNMDA receptor antagonistsDiarylethylaminesFluoroarenesPyrrolidinesNervous system drug stubs


dissociativeanestheticdesigner drugantagonistsNMDA receptorneurotoxicdepressionsympathomimetic













Fluorolintane
Fluorolintane structure.png
Identifiers
ChemSpider
  • 58838621
Chemical and physical data
Formula
C18H20FN
Molar mass
7002269363000000000♠269.363 g·mol−1
3D model (JSmol)
  • Interactive image

Fluorolintane (also known as 2-FPPP) is a dissociative anesthetic drug that has been sold online as a designer drug.[1][2]


Fluorolintane and related diarylethylamines are antagonists of the NMDA receptor[3] and have been studied in vitro as potential treatments for neurotoxic injury,[4]depression[5] and as sympathomimetic.[6]



See also


  • AD-1211

  • Diphenidine

  • Ephenidine

  • Lanicemine


  • Methoxphenidine (MXP)

  • MT-45

  • Prolintane

  • Remacemide


References




  1. ^ Jason Wallach; Pierce V. Kavanagh; Gavin McLaughlin; Noreen Morris; John D. Power; Simon P. Elliott; Marion S. Mercier; David Lodge; Hamilton Morris; Nicola M. Dempster; Simon D. Brandt (May 2014). "Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers". Drug Testing and Analysis. 7 (5): 358–367. doi:10.1002/dta.1689. PMID 25044512..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  2. ^ "Analytical Report - Fluorolintane" (PDF). Nacionalni forenzični laboratorij (NFL). January 2016.


  3. ^ Michael L. Berger; Anna Schweifer; Patrick Rebernik; Friedrich Hammerschmidt (May 2009). "NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds". Bioorganic & Medicinal Chemistry. 17 (1): 3456–3462. doi:10.1016/j.bmc.2009.03.025. PMID 19345586.


  4. ^ Nancy M. Gray; Brian K. Cheng. "Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury". Retrieved 17 June 2015.


  5. ^ Brooke D Aspergren; Richard V Heinzelman (1963). "Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression". Retrieved 22 June 2015.


  6. ^ R. V. Heinzelman; B. D. Aspergren (July 1953). "Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines". Journal of the American Chemical Society. 75 (14): 3409–3413. doi:10.1021/ja01110a033.








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