Fluorolintane See also References Navigation menu58838621Interactive image10.1002/dta.168925044512"Analytical Report - Fluorolintane"10.1016/j.bmc.2009.03.02519345586"Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury""Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression"10.1021/ja01110a033eexpanding ite

Designer drugsDissociative drugsNMDA receptor antagonistsDiarylethylaminesFluoroarenesPyrrolidinesNervous system drug stubs


dissociativeanestheticdesigner drugantagonistsNMDA receptorneurotoxicdepressionsympathomimetic













Fluorolintane
Fluorolintane structure.png
Identifiers
ChemSpider
  • 58838621
Chemical and physical data
Formula
C18H20FN
Molar mass
7002269363000000000♠269.363 g·mol−1
3D model (JSmol)
  • Interactive image

Fluorolintane (also known as 2-FPPP) is a dissociative anesthetic drug that has been sold online as a designer drug.[1][2]


Fluorolintane and related diarylethylamines are antagonists of the NMDA receptor[3] and have been studied in vitro as potential treatments for neurotoxic injury,[4]depression[5] and as sympathomimetic.[6]



See also


  • AD-1211

  • Diphenidine

  • Ephenidine

  • Lanicemine


  • Methoxphenidine (MXP)

  • MT-45

  • Prolintane

  • Remacemide


References




  1. ^ Jason Wallach; Pierce V. Kavanagh; Gavin McLaughlin; Noreen Morris; John D. Power; Simon P. Elliott; Marion S. Mercier; David Lodge; Hamilton Morris; Nicola M. Dempster; Simon D. Brandt (May 2014). "Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers". Drug Testing and Analysis. 7 (5): 358–367. doi:10.1002/dta.1689. PMID 25044512..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  2. ^ "Analytical Report - Fluorolintane" (PDF). Nacionalni forenzični laboratorij (NFL). January 2016.


  3. ^ Michael L. Berger; Anna Schweifer; Patrick Rebernik; Friedrich Hammerschmidt (May 2009). "NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds". Bioorganic & Medicinal Chemistry. 17 (1): 3456–3462. doi:10.1016/j.bmc.2009.03.025. PMID 19345586.


  4. ^ Nancy M. Gray; Brian K. Cheng. "Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury". Retrieved 17 June 2015.


  5. ^ Brooke D Aspergren; Richard V Heinzelman (1963). "Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression". Retrieved 22 June 2015.


  6. ^ R. V. Heinzelman; B. D. Aspergren (July 1953). "Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines". Journal of the American Chemical Society. 75 (14): 3409–3413. doi:10.1021/ja01110a033.








-

Popular posts from this blog

How to get text form Clipboard with JavaScript in Firefox 56?How to validate an email address in JavaScript?How do JavaScript closures work?How do I remove a property from a JavaScript object?How do you get a timestamp in JavaScript?How do I copy to the clipboard in JavaScript?How do I include a JavaScript file in another JavaScript file?Get the current URL with JavaScript?How to replace all occurrences of a string in JavaScriptHow to check whether a string contains a substring in JavaScript?How do I remove a particular element from an array in JavaScript?

Image
Can an x86 CPU running in real mode be considered to be basically an 8086 CPU? Why does this relative pronoun not take the case of the noun it is referring to? Email Account under attack (really) - anything I can do? Why do we use polarized capacitors? N.B. ligature in Latex Is Social Media Science Fiction? how to create a data type and make it available in all Databases? Need help identifying/translating a plaque in Tangier, Morocco How to make payment on the internet without leaving a money trail? What do you call something that goes against the spirit of the law, but is legal when interpreting the law to the letter? How can the DM most effectively choose 1 out of an odd number of players to be targeted by an attack or effect? cryptic clue: mammal sounds like relative consumer (8) Infinite past with a beginning? How do you conduct xenoanthropology after first contact? Is there an example of two elementary particles colliding to result in a single elementar...
Read more

Can't initialize raids on a new ASUS Prime B360M-A motherboard2019 Community Moderator ElectionSimilar to RAID config yet more like mirroring solution?Can't get motherboard serial numberWhy does the BIOS entry point start with a WBINVD instruction?UEFI performance Asus Maximus V Extreme

Image
"One can do his homework in the library" Why does Deadpool say "You're welcome, Canada," after shooting Ryan Reynolds in the end credits? Potential difference and current flow It's a yearly task, alright Co-worker team leader wants to inject the crap software product of his friends into our development. What should I say to our common boss? Touchscreen-controlled dentist office snowman collector game What to do when during a meeting client people start to fight (even physically) with each others? What options are left, if Britain cannot decide? How could our ancestors have domesticated a solitary predator? Professor being mistaken for a grad student When two POV characters meet Replacing Windows 7 security updates with anti-virus? What has been your most complicated TikZ drawing? Can the word "advantage" be used as an adjective? How could a female member of a species produce eggs unto death? Can the druid cantrip Thorn...
Read more

List of MPs elected to the English parliament in 1640 (April) Contents List of constituencies and members See also Notes References Navigation menueNational Archives – The Glynde Place ArchivesCobbett's Parliamentary history of England, from the Norman Conquest in 1066 to the year 1803'Aldermen in Parliament', The Aldermen of the City of London: Temp. Henry III – 1912onepage&q&f&#61, false 229

Image
Parliaments of Charles I of England1640 in England1640 in politicsLists of Members of the Parliament of England (pre-1707)English MPs 1640 (April) King Charles IShort ParliamentLong Parliament Parliaments of England 1604–1705 Parliament Date Blessed Parliament 1604 Addled Parliament 1614 3rd Parliament of King James I 1621 Happy Parliament 1624 Useless Parliament 1625 2nd Parliament of King Charles I 1626 3rd Parliament of King Charles I 1628 Short Parliament 1640 Apr Long Parliament (1) 1640 Nov Oxford Parliament 1644 Long Parliament (2) 1645 Rump Parliament (1) 1648 Barebone's Parliament 1653 First Protectorate Parliament 1654 Second Protectorate Parliament 1656 Third Protectorate Parliament 1659 Rump Parliament (2) 1659 Long Parliament (3) 1660 Convention Parliament 1660 Cavalier Parliament 1661 Habeas Corpus Parliament 1679 Exclusion Bill Parliament 1680 Oxford Parliament 1681 Loyal Parliament 1685 Convention Parliament 1689...
Read more