FGF-1 internal ribosome entry site (IRES) References External links Navigation menuRF0038700430220000243PDBe"Internal Ribosome Entry Site Structural Motifs Conserved among Mammalian Fibroblast Growth Factor 1 Alternatively Spliced mRNAs"10.1128/MCB.24.17.7622-7635.200450700815314170Page for FGF-1 internal ribosome entry site (IRES)expanding ite

Cis-regulatory RNA elementsMolecular and cellular biology stubs


RNA element5' UTRmRNAfibroblast growth factorinternal ribosome entry site


















FGF-1 internal ribosome entry site (IRES)

RF00387.jpg
Predicted secondary structure and sequence conservation of IRES_FGF1

Identifiers
SymbolIRES_FGF1
RfamRF00387
Other data

RNA type
Cis-reg; IRES
Domain(s)Eukaryota
GO0043022
SO0000243

PDB structures		PDBe

The FGF-1 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of fibroblast growth factor-1 and allows cap-independent translation. It is thought that FGF-1 internal ribosome entry site (IRES) activity is strictly controlled and highly tissue specific.[1]



References



  1. ^ Martineau, Y; Le Bec C; Monbrun L; Allo V; Chiu IM; Danos O; Moine H; Prats H; Prats AC (2004). "Internal Ribosome Entry Site Structural Motifs Conserved among Mammalian Fibroblast Growth Factor 1 Alternatively Spliced mRNAs". Mol Cell Biol. 24 (17): 7622–7635. doi:10.1128/MCB.24.17.7622-7635.2004. PMC 507008. PMID 15314170..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em



External links





  • Page for FGF-1 internal ribosome entry site (IRES) at Rfam




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